Da Huang (Zhi)
Granule SingleHerbs

Da Huang (Zhi)

酒大黄

Radix et Rhizoma Rhei(stir-fried with wine)

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SKU: D0560
80139730
Concentration Ratio: 6:1

Description

Rhei Radix et Rhizoma (Processed with Wine) Stir-bake the slices as described under the method for stir-baking with wine (0213) until dry. Description Similar to the slices of Rhei Radix et Rhizoma. Externally dark brownish-yellow, some with slight scorched patches. Odour slightly wine-like and aromatic. Identification As required for the crude drug. Rhaponticin As required for the crude drug. Water Not more than 13.0%. Total Ash As required for the crude drug. Extractives As required for the crude drug. Assay Total Anthraquinone As required for the crude drug. Free Anthraquinone Not less than 0.50%. Rhei Radix et Rhizoma (Prepared) Stew or steam the pieces as described under the method for stewing or steaming with wine (0213) until thoroughly darkened. Description Irregular pieces. Externally black. Radial striations indistinct on the fractured surface. Texture hard. Odour slightly aromatic. Identification As required for the crude drug. Rhaponticin As required for the crude drug. Water Not more than 13.0%. Total Ash As required for the crude drug. Extractives As required for the crude drug. Assay Total Anthraquinone As required for the crude drug. Free Anthraquinone Not less than 0.50%. Rhei Radix et Rhizoma (Carbonized) Stir-bake the slices as described under the method for carbonizing by stir-baking (0213) until the outer surface is charred and the interior becomes dark brown. Description Similar to the prepared slices. Externally charred black. Interior dark brown to charred brown. Odour charred and aromatic. Identification Identification (2) and (3): As required for the crude drug. Rhaponticin As required for the crude drug. Water As required for the crude drug. Total Ash As required for the crude drug. Extractives As required for the crude drug. Assay Total Anthraquinone Not less than 0.90%. Free Anthraquinone Not less than 0.50%.

中文说明

[性味归经]:寒,苦。归脾、胃、大肠、肝、心、三焦、小肠、膀胱经。沉。 用法用量:煎服,3-30克,用于泻下不宜久煎;研末服,1-3克。酒炒,上达巅顶;酒洗,中至胃脘;生用,下行。凡表证未罢,血气虚弱、脾胃虚寒,无实热、积滞、瘀结者,以及妇女怀孕、月经期、哺乳期应慎用或忌用。 [功效主治]:1,泻热,润肠,泻下攻积,用于肠道积滞,大便秘结。2,凉血泻火,用于血热妄行之吐血,衄血,火邪上炎之目赤,咽痛,牙龈肿痛等。3,清热解毒,用于热毒疮疡及烧伤等。4,活血祛瘀通经,用于妇女瘀血闭经,产后恶露不下,症瘕积聚,跌打损伤。 [现代研究]: 本品含有蒽醌类化合物约3%,包括游离状态和结合状态大黄酸、大黄酚、大黄素、芦荟大黄素、大黄素甲醚、蜈蚣苔素,其主要的泻下成分为结合性大黄酸蒽酮-番泻甙A、B、C,其中番泻甙A为主要有效成分。此外,尚含鞣质约5%以及游离没食子酸、桂皮酸及其酯类等。叶含槲皮甙,惟掌叶大黄的叶以金丝桃甙含量最多。 1,掌叶大黄及唐古特大黄泻下的有效成分是结合状态的大黄酸和其类似物。本品因含鞣质及没食子酸等,又具收敛作用,故大剂量使用大黄时先泻后便秘。若煎药时间过长,则蒽醌类化合物及结合性大黄酸和其类似物破坏较多,鞣酸等成分大量煎出,故仅有致便秘作用,而无泻下作用。2,有增加血小板、促进血液凝固等止血作用。3,本品可促进胆汁等消化液分泌,有利胆、排石和增进消化作用。4,保肝作用:有抗中毒性肝炎的作用,使SGPT明显下降。大黄注射液对急性黄疸性肝炎有明显的退黄作用。5,解热作用:大黄能使感染性发热患者和动物体温下降;可使发热家兔第三脑室灌流液内前列腺素E水平下降。6,抗炎作用:大黄煎剂对多种不同炎症模型均有显著的对抗作用,对以渗出和肉芽增生为主的炎症过程均有抑制作用。7,降压作用:大黄酊剂、浸剂经家兔试验有降压作用,其中以酊剂效果较好。8,大黄素对抗乙酰胆碱引起的小鼠离体肠痉挛作用强于对抗豚鼠气管痉挛的作用。9,本品有降低血清高胆固醇的作用。10,掌叶大黄及大黄酸、大黄素均有利尿作用,以大黄酸作用最强。11,大黄在体内可辅助病毒诱生干扰素,增加人体白细胞干扰素诱导效价,提高患者体内干扰素水平。12,大黄对慢性肾功能不全大鼠,可明显降低血中尿素氮及肌酐含量。13,大黄能提高小鼠腹腔巨噬细胞的吞噬功能。14,大黄对大鼠实验性胃溃疡有保护作用。15,大黄水煎液对小